| Date | Player | Pos. | Transaction |
| 5/10 | Chuck James | P | Called Up from Minors |
| 5/10 | Buddy Carlyle | P | Placed on 15-Day DL, (Strained neck muscle) |
| 5/8 | Omar Infante | 2B | Recalled From Minors, Rehab Assignment |
| 5/8 | Omar Infante | 2B | Removed From 15-Day DL, (Broken left hand) |
| 5/8 | Brayan Pena | C | Placed on 15-Day DL, (Back strain) |
| 5/5 | Omar Infante | 2B | Sent to Minors, For Rehabilitation |
| 5/5 | Peter Moylan | P | Transferred to 60-Day DL, (Right elbow surgery - out for season) |
| 5/5 | Martin Prado | 2B | Placed on 15-Day DL, (Sprained left thumb) |
| 5/5 | Greg Norton | 1B | Traded From, Seattle (for future considerations) |
| 5/3 | Julio Franco | 1B | Retired |
| 5/3 | Brent Lillibridge | SS | Sent to Minors |
| 5/3 | Jo-Jo Reyes | P | Called Up from Minors |
| 4/29 | John Smoltz | P | Placed on 15-Day DL, (Right shoulder inflammation) |
| 4/29 | Tom Glavine | P | Removed From 15-Day DL, (Strained right hamstring) |
| 4/26 | Scott Williamson | P | Signed to a Minor League Contract |
| 4/26 | Brent Lillibridge | SS | Purchased From Minors |
| 4/26 | Phil Stockman | P | Sent to Minors |
| 4/25 | Mike Hampton | P | Sent to Minors, For Rehabilitation |
| 4/25 | Phil Stockman | P | Called Up from Minors |
| 4/24 | Chuck James | P | Sent to Minors |
| 4/19 | Chuck James | P | Called Up from Minors |
| 4/19 | Tom Glavine | P | Placed on 15-Day DL, (Strained right hamstring) |
| 4/15 | Buddy Carlyle | P | Called Up from Minors |
| 4/15 | Peter Moylan | P | Placed on 15-Day DL, (Bone spur, right elbow) |
| 4/12 | Scott Spiezio | 3B | Released |
| 4/11 | Chuck James | P | Sent to Minors |
| 4/11 | Jorge Campillo | P | Purchased From Minors |
| 4/9 | Rafael Soriano | P | Placed on 15-Day DL, (Right elbow tendinitis) |
| 4/9 | Chuck James | P | Removed From 15-Day DL, (Recovery from torn rotator cuff) |
| 4/6 | Jo-Jo Reyes | P | Sent to Minors |
| 4/6 | John Smoltz | P | Removed From 15-Day DL, (Right shoulder inflammation) |
| 4/4 | Sal Fasano | C | Signed to a Minor League Contract |
| 4/4 | Mike Hampton | P | Placed on 15-Day DL, (Strained left pectoral) |
| 4/4 | Jo-Jo Reyes | P | Called Up from Minors |
| 3/31 | Scott Spiezio | 3B | Signed to a Minor League Contract |
| 3/29 | Josh Anderson | LF | Sent to Minors |
| 3/29 | Buddy Carlyle | P | Sent to Minors |
| 3/22 | Mike Gonzalez | P | Placed on 15-Day DL, (Recovery from left elbow surgery) |
| 3/22 | Omar Infante | 2B | Placed on 15-Day DL, (Broken left hand) |
| 3/22 | Javy Lopez | C | Retired |
| 3/22 | Anthony Lerew | P | Placed on 60-Day DL, (Recovery from left elbow surgery) |
| 3/22 | Brandon Jones | LF | Sent to Minors |
| 3/22 | Jo-Jo Reyes | P | Sent to Minors |
| 3/12 | Phil Stockman | P | Sent to Minors |
| 2/14 | Damian Moss | P | Signed to a Minor League Contract |
| 2/8 | Matt DeSalvo | P | Signed to a Minor League Contract |
| 1/24 | Rafael Soriano | P | Signed, ( 2008-2009)(two-year extension) |
| 1/18 | Matt Diaz | LF | Signed, ( 2008)(avoids arbitration) |
| 1/17 | Jeff Ridgway | P | Traded From, Tampa Bay (for 3B Willy Aybar and SS Chase Fontaine) |
| 1/17 | Mike Gonzalez | P | Signed, ( 2008)(avoids arbitration) |
| 1/17 | Tyler Yates | P | Signed, ( 2008)(avoids arbitration) |
| 1/17 | Mark Teixeira | 1B | Signed, ( 2008)(avoids arbitration) |
| 1/17 | Omar Infante | 2B | Signed, ( 2008)(avoids arbitration) |
| 1/14 | Mark Kotsay | CF | Traded From, Oakland (for RHPs Joey Devine & Jamie Richmond) |
| 1/13 | Mark Kotsay | CF | Traded From, Oakland (for RHP Joey Devine) |
| 12/17 | Jorge Campillo | P | Signed to a Minor League Contract |
| 12/17 | Javy Lopez | C | Signed to a Minor League Contract |
| 12/17 | Corky Miller | C | Signed to a Minor League Contract |
| 12/17 | Joe Borchard | RF | Signed to a Minor League Contract |
| 12/12 | Willie Harris | LF | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/12 | Seth Greisinger | P | Signed to Play in Japan, (Yomiuri Giants) |
| 12/7 | Lance Cormier | P | Released |
| 12/4 | Will Ohman | P | Traded From, Chi. Cubs (w/SS Omar Infante for RHP Jose Ascanio) |
| 12/4 | Omar Infante | 2B | Traded From, Chi. Cubs (with P Will Ohman for RHP Jose Ascanio) |
| 12/4 | Willie Harris | LF | Designated for Assignment |
| 11/30 | Lance Cormier | P | Designated for Assignment |
| 11/28 | Pete Orr | 3B | Released |
| 11/20 | Pete Orr | 3B | Designated for Assignment |
| 11/18 | Tom Glavine | P | Signed as Free Agent, ( 2008) |
| 11/16 | Josh Anderson | LF | Traded From, Houston (for RHP Oscar Villarreal) |
| More Transactions |
| Posted Sun May 11 20:05:14 EDT 2008 |
