| Date | Player | Pos. | Transaction |
| 5/6 | Kory Chapman | RB | cut |
| 5/2 | Steve Cargile | S | acquired from waivers |
| 3/28 | Seth McKinney | C | re-signed/unrestricted free agent, One-year contract |
| 3/26 | Kris Griffin | LB | signed, One-year contract |
| 3/21 | Shantee Orr | LB | signed/unrestricted free agent, One-year contract |
| 3/13 | Charles Ali | RB | signed |
| 3/13 | Gary Baxter | CB | re-signed/unrestricted free agent, One-year contract |
| 3/10 | Rex Hadnot | C | signed/unrestricted free agent, Two-year contract |
| 3/10 | Lennie Friedman | G | re-signed/unrestricted free agent, One-year contract |
| 3/5 | Shaun Rogers | DT | signed, Six-year contract |
| 3/4 | Nick Sorensen | S | re-signed/unrestricted free agent, Three-year contract |
| 3/2 | Corey Williams | DT | traded, For 2nd-round draft pick in 2008 |
| 3/1 | Donte' Stallworth | WR | signed/unrestricted free agent, Seven-year contract |
| 2/29 | Ricardo Colclough | CB | declared free agent |
| 2/29 | Nat Dorsey | T | declared free agent |
| 2/29 | Tim Carter | WR | declared free agent |
| 2/29 | Gary Baxter | CB | declared free agent |
| 2/29 | Keith Adams | LB | declared free agent |
| 2/27 | Orpheus Roye | DT | cut |
| 2/22 | Jamal Lewis | RB | re-signed, Three-year contract |
| 12/26 | Bobby Hamilton | DE | signed |
| 12/26 | Ken Dorsey | QB | signed, three-year extension |
| 12/26 | Zach West | DT | practice squad addition |
| 12/26 | Mel Purcell | DE | Activated from the Practice Squad |
| 12/24 | Ethan Kelley | DT | Placed on IR, knee |
| 12/24 | Mike Adams | S | Placed on IR, knee |
| 12/12 | Brad Cieslak | TE | practice squad addition |
| 12/12 | Jonny Harline | TE | practice squad deletion |
| 12/12 | Colby Bockwoldt | LB | cut |
| 12/12 | Greg Eslinger | C | cut |
| 12/12 | Keith Adams | LB | signed |
| 12/11 | Marvin Philip | C | signed |
| 12/11 | Jonny Harline | TE | practice squad deletion |
| 12/5 | Colby Bockwoldt | LB | signed |
| 12/5 | Kris Griffin | LB | Placed on IR, right knee |
| 11/28 | Kory Chapman | RB | practice squad addition |
| 11/28 | Jonny Harline | TE | practice squad addition |
| 11/14 | Greg Eslinger | C | signed/unrestricted free agent |
| More Transactions |
| Posted Thu May 08 11:19:35 EDT 2008 |
