| Date | Player | Pos. | Transaction |
| 4/30 | Artose Pinner | RB | signed, One-year contract |
| 4/22 | Stephen Peterman | G | re-signed/restricted free agent, One-year contract |
| 4/22 | Dan Orlovsky | QB | re-signed/restricted free agent, One-year contract |
| 4/22 | Langston Moore | DT | re-signed/restricted free agent, One-year contract |
| 4/11 | Patrick Body | CB | cut |
| 4/11 | Stanley Wilson | CB | re-signed/restricted free agent, One-year contract |
| 4/11 | Paul Ernster | P | signed, One-year contract |
| 3/28 | Kalimba Edwards | DE | signed, Two-year contract |
| 3/24 | Gilbert Gardner | LB | signed/unrestricted free agent, One-year contract |
| 3/17 | Corey Smith | DE | signed, One-year contract |
| 3/14 | Kenoy Kennedy | S | cut |
| 3/13 | Kalimba Edwards | DE | cut |
| 3/13 | Kevin Jones | RB | cut |
| 3/12 | Blaine Saipaia | G | cut |
| 3/12 | Travis Fisher | CB | re-signed/unrestricted free agent, Three-year contract |
| 3/10 | Tatum Bell | RB | re-signed/unrestricted free agent, One-year contract |
| 3/10 | George Foster | T | re-signed/unrestricted free agent, One-year contract |
| 3/8 | Brian Kelly | CB | signed/unrestricted free agent, Three-year contract |
| 3/7 | Chuck Darby | DT | signed/unrestricted free agent, Three-year contract |
| 3/6 | Kalvin Pearson | S | signed/offer sheet, Three-year contract |
| 3/5 | Corey Hulsey | G | signed/unrestricted free agent, One-year contract |
| 3/5 | Aveion Cason | RB | re-signed/unrestricted free agent |
| 3/3 | John Owens | TE | re-signed/unrestricted free agent, One-year contract |
| 3/3 | Michael Gaines | TE | signed/unrestricted free agent, Four-year contract |
| 3/1 | Leigh Bodden | CB | traded, with draft pick for Shaun Rogers |
| 2/28 | Keith Smith | CB | re-signed/unrestricted free agent, Two-year contract |
| 2/27 | Dwight Smith | S | signed, Two-year contract |
| 2/25 | Fernando Bryant | CB | cut |
| 2/25 | Devale Ellis | WR | Activated from the physically unable to perform list |
| 12/21 | Shirdonya Mitchell | CB | practice squad deletion |
| 12/20 | Victor DeGrate | DE | practice squad deletion |
| 12/20 | Shirdonya Mitchell | CB | practice squad addition |
| 12/19 | Roy Williams | WR | Placed on IR, right knee |
| 12/19 | Buster Davis | LB | Activated from the Practice Squad |
| 12/19 | Claude Harriott | DE | practice squad addition |
| 12/14 | Patrick Body | CB | Activated from the Practice Squad |
| 12/5 | LaMarcus Hicks | CB | Placed on IR, ankle |
| 12/5 | Brandon Middleton | WR | Activated from the Practice Squad |
| 12/5 | Reggie Ball | WR | practice squad addition |
| 11/29 | Ramzee Robinson | CB | Activated from the Practice Squad |
| 11/26 | Jonathan Scott | T | Placed on IR, Hand |
| 11/26 | Barry Stokes | G | signed |
| 11/26 | Victor DeGrate | DE | practice squad addition |
| 11/20 | Greg Blue | S | signed/unrestricted free agent |
| 11/19 | Idrees Bashir | S | Placed on IR, knee |
| 11/19 | Rudy Sylvan | TE | practice squad deletion |
| 11/14 | Rudy Sylvan | TE | practice squad addition |
| 11/13 | Rudy Sylvan | TE | cut |
| 11/13 | John Owens | TE | signed |
| 11/11 | Rudy Sylvan | TE | Activated from the Practice Squad |
| More Transactions |
| Posted Fri May 02 22:19:33 EDT 2008 |
