| Date | Player | Pos. | Transaction |
| 5/2 | Jonathan Lewis | DT | cut |
| 5/2 | Floyd Womack | G | re-signed/unrestricted free agent, One-year contract |
| 4/30 | Larry Tripplett | DT | signed |
| 4/30 | Dalton Bell | QB | acquired from waivers |
| 4/30 | Wesly Mallard | LB | signed |
| 4/23 | Shaun Alexander | RB | cut |
| 4/7 | Omare Lowe | S | signed/unrestricted free agent, One-year contract |
| 3/27 | Olindo Mare | K | signed, Two-year contract |
| 3/26 | Marcus Trufant | CB | re-signed, Six-year contract |
| 3/25 | D.D. Lewis | LB | signed, One-year contract |
| 3/25 | Chris Cooper | DE | signed, One-year contract |
| 3/21 | Lofa Tatupu | LB | signed, Six-year contract extension |
| 3/8 | Julius Jones | RB | signed/unrestricted free agent, Four-year contract |
| 3/5 | T.J. Duckett | RB | signed/unrestricted free agent, Five-year contract |
| 3/4 | Jeb Putzier | TE | signed, One-year contract |
| 2/21 | Marcus Trufant | CB | Designated franchise player |
| 1/1 | Kelly Talavou | DT | practice squad addition |
| 1/1 | Logan Payne | WR | Activated from the Practice Squad |
| 1/1 | Baraka Atkins | DE | Placed on IR, ankle |
| 12/11 | Jeff Robinson | TE | signed |
| 12/11 | Boone Stutz | TE | cut |
| 12/5 | Omowale Dada | CB | practice squad addition |
| 12/5 | Kevin Hobbs | CB | Activated from the Practice Squad |
| 12/4 | Josh Scobey | RB | signed |
| 12/4 | Fred McCrary | RB | cut |
| 12/4 | C.J. Wallace | S | Placed on IR, knee |
| 11/15 | Kevin Hobbs | CB | practice squad addition |
| 11/13 | Kevin Hobbs | CB | cut |
| 11/12 | David Kirtman | RB | Activated from the Practice Squad |
| More Transactions |
| Posted Sun May 04 22:34:34 EDT 2008 |
